Posts Tagged ‘biology’
Cell and Systems Biology – University of Toronto
The Department of Cell & Systems Biology at the University of Toronto invites applications for a tenure track faculty position to be appointed at the level of Assistant or Associate Professor beginning July 1, 2011.
We are interested in outstanding candidates that complement existing strengths in the department in the areas of genomics, plant and microbial biology, cell and developmental biology, and neurosciences using high-throughput approaches or gene/protein network analyses with genom…
Postdoc Position Systems Biology of African trypanosomes (SilicoTryp)
Based on the information generated by the experimental partners, the postdoc will build a computational model that will integrate redox and energy metabolism with signal transduction and gene expression. The postdoc will collaborate with other theoreticians as well as with experimental partners….
Research Faculty Computational and Systems Biology
The Computational Biology Program (http://cbio.mskcc.org) at MSKCC (mskcc.org) seeks innovative investigators for tenure-track positions at the Assistant, Associate, or Full Professor level. Pursue basic research, solve biological problems with major emphasis on computational methods, and build active bridges to experimental and clinical research. Actively participate in building out research programs at one of the best clinical-scientific institutions in the world. Work in MSKCC’s new Zuckerman Research Center, on Manhattan’s Upper East Side, in close proximity to Rockefeller University and the Cornell Weill Medical College. Train graduate students in the Gerstner Sloan-Kettering Graduate School (sloankettering.edu), the Weill Cornell Graduate School of Medical Sciences and in tri¬-institutional graduate programs.
Areas of special interest include chemical biology, physiology, developmental biology, neurobiology, genetics and cancer biology. Applicants should have a doctoral-level degree and the potential to develop an independent, interdisciplinary research program. MSKCC offers a highly interactive, supportive and dynamic research environment with programs in Computational Biology, Developmental Biology,
Molecular Pharmacology & Chemistry, Cancer Biology & Genetics, Structural Biology, Immunology, Cell Biology, Molecular Biology, and Human Oncology and Pathogenesis, as well as unparalleled clinical programs in cancer research, treatment and prevention.
The deadline for applications is November 1, 2010. Please visit www.cbio.mskcc.org/faculty-search for specific application instructions including the required IMPACT format of your bibliography. To access the on-line faculty application, go to http://facultysearch.ski.edu.
Please visit the site as soon as possible, as it contains important information on the required application materials, including deadlines for submission of letters of reference. Inquiries may be sent to Chris Sander, Chair, Computational Biology Program via Dwana Agosto, Program Coordinator, at agostod@mskcc.org.
MSKCC is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply.
The Erasmus MC plans to appoint a ‘Ph.D. student (OIO)’ for the department Cell biology.
In the current project we will apply state of the art gene delivery technology and experimental therapeutics to reduce lung disease in the mutant mouse model. Further, the program will use advanced 3D culture of human airway cells to analyse the mechanism of inflammation and fibrosis.
Are you a highly motivated graduate in biomedical sciences, biology or biochemistry with a background in bioinformatics, epidemiology, genetics and/or statistics?
You will be using advanced statistical and bioinformatics techniques to investigate the genetic architecture of cardiovascular disease (e.g. stroke, coronary heart disease and peripheral artery disease) using data from the SMART study (Second Manifestations of Arterial Disease). The goal is to gain…
The Alternatives Unit at the Biomedical Primate Research Centre (BPRC) is seeking an AiO/PhD student (Immunology/Cell Biology) for a 4-year project on inflammasome-mediated cellular activation in the brain.
Your profile is that of a highly motivated young professional with an MSc. in (medical) biology, biochemistry or medicine. Expertise in cell culture and immunological, molecular biological and/or biochemical techniques is a prerequisite. You are energetic, curious and up-to-the-job and have an open mind with an intrinsic interest in problem solving.
Our research focuses on the role of brain tissue cells, such as astrocytes and microglia, in neuroinflammatory diseases as multiple sclerosis (MS). One of the hallmarks of MS pathology is the presence of activated microglia.
In this project, we will use in vitro primary cell cultures to study microglia activation via recently identified receptors of the innate immune system that can form inflammasomes. The involvement of inflammasomes in the development of MS lesions and of other neuroinflammatory disorders will be investigated by in situ analysis of human brain sections. In addition, we will search for mechanisms to halt microglia activation, with the ultimate aim to identify novel possibilities for therapeutical intervention.
Sanquin has got an opening for a PhD Student Sanquin, Dept. of Blood Cell Research, which is focused on the biology and role of blood cells, amongst them phagocytes, red blood cells and platelets.
PhD student in the recently started research group of dr. L. Gutierrez-Gutierrez, to perform research on the project: “Transcriptome-wise dendritic cell manipulation”. In this project, we aim to unravel the role of Gata1 in the development, generation and function of dendritic cells. With this purpose, we make use of transgenic mouse models, proteomics, molecular biology and bioinformatics.
The Netherlands Cancer Institute – Antoni van Leeuwenhoek Hospital (NKI-AVL) has a vacancy at the central Microarray and Deep Sequencing Facility for a fulltime Molecular Biology Technician – Amsterdam, the Netherlands.
As a technician within the facility you will be involved in preparing DNA and RNA samples for a range of microarray platforms and next-generation sequencing experiments. You will be using a range of molecular biology techniques for this. Furthermore, you will assist in quantification of the data using several software tools and preparing the data for further analysis by the researcher using our own database. Finally, you will be involved in optimizing existing techniques and implementing new ones. You should in time be able to transfer your knowledge about the techniques, equipment and analysis to the researchers using the facility.
The Central Microarray and Deep Sequencing Facility supports all researchers at the NKI during their experiments involving microarray and next-generation sequencing analysis. The facility gives advise, performs experiments and helps in the analysis of the data.
The facility consists of a modern lab with highly advanced techniques and equipment for genome analysis and the team consists of a group of enthusiastic, young people. The facility is supervised by dr. Ron Kerkhoven and there are 3 technicians and 3 bioinformaticians.
Group Head, in vitro Biology
Affitech AS is a publicly traded (NASDAQ OMX Copenhagen) human therapeutic antibody company headquartered in Copenhagen, Denmark with R&D facilities in Oslo, Norway (Affitech Research AS), close to one of the largest universities in Scandinavia and the Norwegian National Hospital. The company utilizes a range of proprietary antibody technologies for the discovery of fully human antibodies for application in oncology, inflammation and other disease areas. CBAS™ (Cell Based Antibody Select…
PhD Researcher within the Theoretical Biology and Bioinformatics Group (1,0 fte)
Modelling asymmetric cell division in C. elegans.
Asymmetric cell division is crucial for generating cell type diversity during development, and for enabling stem cells to combine self-renewal with the production of differentiating daughter cells. During asymmetric cell division the cleavage plane is positioned such that an unequal distribution of cellular components over daughter cells is achieved, allowing them to adopt different fates.
In this project the PhD student will collaborate intensively with the experimental developmental biology group of Prof S. van den Heuvel studying asymmetric cell division in C. elegans. The PhD student will integrate their experimental data into a computational modelling framework in which cell shape, membrane properties, gene regulation, protein phosphorylation, protein localization and spindle positioning are taken into account. The model will be used to obtain more insight in the mechanisms controlling cleavage plane positioning.
One important research question the PhD will study concerns the mechanisms and forces that control the sequence of rotation, centration and posterior displacement of the centrosomes and spindle observed during the autonomous asymmetric division of the single cell zygote (1). Another research question concerns how the asymmetric division of epithelial seam cells depends on cell shape and polarity and how these in turn depend on cell-cell and cell-extracellular matrix adhesion and signalling.
(1) Galli M, van den Heuvel S. Determination of the Cleavage Plane in Early C. elegans embryos. Annu Rev Genet. 2008;42:389-411.